COG0001 - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
some 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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Gene Fusion

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Score

COG0001

Glutamate-1-semialdehyde aminotransferase

Predicted Functional Partners:

COG0373

0.967

COG1020

0.942

COG3321

0.931

COG1648

0.930

COG0113

0.929

COG1861

0.920

COG0181

0.919

COG0500

0.910

COG1587

0.904

COG0318

0.887

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
COG0001	COG0113	COG0001 - Glutamate-1-semialdehyde aminotransferase	COG0113 - Delta-aminolevulinic acid dehydratase, porphobilinogen synthase	0.929
COG0001	COG0181	COG0001 - Glutamate-1-semialdehyde aminotransferase	COG0181 - Porphobilinogen deaminase	0.919
COG0001	COG0318	COG0001 - Glutamate-1-semialdehyde aminotransferase	COG0318 - Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II	0.887
COG0001	COG0373	COG0001 - Glutamate-1-semialdehyde aminotransferase	COG0373 - Glutamyl-tRNA reductase	0.967
COG0001	COG0500	COG0001 - Glutamate-1-semialdehyde aminotransferase	COG0500 - SAM-dependent methyltransferase	0.910
COG0001	COG1020	COG0001 - Glutamate-1-semialdehyde aminotransferase	COG1020 - Non-ribosomal peptide synthetase component F	0.942
COG0001	COG1587	COG0001 - Glutamate-1-semialdehyde aminotransferase	COG1587 - Uroporphyrinogen-III synthase	0.904
COG0001	COG1648	COG0001 - Glutamate-1-semialdehyde aminotransferase	COG1648 - Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain)	0.930
COG0001	COG1861	COG0001 - Glutamate-1-semialdehyde aminotransferase	COG1861 - Spore coat polysaccharide biosynthesis protein SpsF, cytidylyltransferase family	0.920
COG0001	COG3321	COG0001 - Glutamate-1-semialdehyde aminotransferase	COG3321 - Acyl transferase domain in polyketide synthase (PKS) enzymes	0.931
COG0113	COG0001	COG0113 - Delta-aminolevulinic acid dehydratase, porphobilinogen synthase	COG0001 - Glutamate-1-semialdehyde aminotransferase	0.929
COG0113	COG0181	COG0113 - Delta-aminolevulinic acid dehydratase, porphobilinogen synthase	COG0181 - Porphobilinogen deaminase	0.981
COG0113	COG0373	COG0113 - Delta-aminolevulinic acid dehydratase, porphobilinogen synthase	COG0373 - Glutamyl-tRNA reductase	0.947
COG0113	COG0500	COG0113 - Delta-aminolevulinic acid dehydratase, porphobilinogen synthase	COG0500 - SAM-dependent methyltransferase	0.720
COG0113	COG1020	COG0113 - Delta-aminolevulinic acid dehydratase, porphobilinogen synthase	COG1020 - Non-ribosomal peptide synthetase component F	0.494
COG0113	COG1587	COG0113 - Delta-aminolevulinic acid dehydratase, porphobilinogen synthase	COG1587 - Uroporphyrinogen-III synthase	0.967
COG0113	COG1648	COG0113 - Delta-aminolevulinic acid dehydratase, porphobilinogen synthase	COG1648 - Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain)	0.851
COG0113	COG1861	COG0113 - Delta-aminolevulinic acid dehydratase, porphobilinogen synthase	COG1861 - Spore coat polysaccharide biosynthesis protein SpsF, cytidylyltransferase family	0.451
COG0113	COG3321	COG0113 - Delta-aminolevulinic acid dehydratase, porphobilinogen synthase	COG3321 - Acyl transferase domain in polyketide synthase (PKS) enzymes	0.508
COG0181	COG0001	COG0181 - Porphobilinogen deaminase	COG0001 - Glutamate-1-semialdehyde aminotransferase	0.919

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